Analytical Standards

HPLC detector equipment in a pharmaceutical quality-control laboratory

HPLC Method Development for Food and Beverage Analysis: Practical Guide

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HPLC method development for food and beverage analysis starts with a defined analyte, food matrix and decision the result must support. A method for vitamins in juice may not be suitable for preservatives in soft drinks or contaminants in oils. This practical guide covers analytical goals, sample preparation, chromatographic conditions, validation, quality control and regulatory […]

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USGS scientist operating a high-performance liquid chromatography (HPLC) system in a laboratory

HPLC Method Development for Pharmaceutical Analysis: A GMP Guide

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HPLC method development for pharmaceutical analysis is a planned, evidence-based process for creating a chromatographic procedure that is fit for its intended use. This guide explains how pharmaceutical QC and analytical development teams can define the method objective, select chromatographic conditions, prepare samples, evaluate performance and document decisions within the site quality system. Educational scope:

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